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pentobarbital will decrease the level or result of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.

pentobarbital will lessen the level or impact of pimozide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.

Contraindicated (1)pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can reduce panobinostat degrees by ~70% and bring on therapy failure.

pentobarbital will lessen the level or outcome of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will minimize the extent or outcome of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

pentobarbital decreases levels of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Keep away from Unless of course the coadministration outweighs the possible hazard of ponatinib underexposure; keep an eye on for signs of reduced efficacy.

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pentobarbital will minimize the level or impact of dapsone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.

pentobarbital will lessen the extent or outcome of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Powerful CYP3A4 inducers are predicted to induce substantial decreases in sildenafil plasma ranges

pentobarbital will reduce the extent or effect of conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will lower the extent or impact of vincristine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.

pentobarbital will reduce the level or result of budesonide by influencing hepatic/intestinal enzyme click here CYP3A4 metabolism. Use Warning/Monitor.

pentobarbital will decrease the level or outcome of midostaurin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Powerful CYP3A4 inducers may possibly decrease midostaurin concentrations leading to decreased efficacy.

Monoamine oxidase inhibitors (MAOI) may inhibit barbiturate metabolism and prolong barbiturate effects; monitor closely